Dynamic Drug Advancement Limited | Durham Institute of Respirology
COPD Clinical Research Studies
Breztri NGP
Assessing a new generation, environmentally friendly propellant known as HFO (hydrofluoroolefin) in the Breztri inhaler. This study is for patients with Moderate to Very Severe
​
​
AERIFY
Utilization of Itepekimab in Patients With Moderate-to-severe Chronic Obstructive Pulmonary Disease (COPD)
​
​
Mechanism: Anti-IL-33
​
CONTACT US​
ARNASA
Utilization of Astegolimab in Patients with Chronic Obstructive Pulmonary Disease With a History of Exacerbations
​
Mechanism: Anti-IL-33
​
NOTUS
Utilization of Dupilumab in Patients With Moderate to Severe COPD With Type 2 Inflammation.
​
Mechanism: Anti-Il-4
RESOLUTE
Utilization of Benralizumab in Moderate to Very Severe Chronic Obstructive Pulmonary Disease (COPD) With a History of Frequent Exacerbations
​
Mechanism: Anti-IL-5
​​
MATINEE
Utilization of Mepolizumab as Add-on Treatment In Patients With COPD Characterized by Frequent Exacerbations and Eosinophil Level
​
Mechanism: Anti-IL-5
​
OBERON
Utilization of Tozorakimab in Patients with Chronic Obstructive Pulmonary Disease With a History of Exacerbations
​
Mechanism: Anti-IL-33
​
Asthma Clinical Research Studies
NIMBLE
Utilization of Depemokimab Compared With Mepolizumab or Benralizumab in Participants With Severe Asthma With an Eosinophilic Phenotype
​
Mechanism: Anti-IL-5
KALOS
Utilization of Budesonide, Glycopyrronium, and Formoterol Fumarate metered dose inhaler relative to Budesonide and Formoterol Fumarate MDI and Symbicort® pressurized MDI in patients with inadequately controlled asthma
​
ATLAS
Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Patients With Uncontrolled Moderate to Severe Asthma
​
Mechanism: Anti-IL-4
VATHOS
Utilization of Budesonide and Formoterol Fumarate Metered Dose Inhaler Relative to Budesonide Metered Dose Inhaler and Open-Label Symbicort® Turbuhaler® in Adult and Adolescent Patients With Inadequately Controlled Asthma
​
CONTACT US
SUNRISE
Utilizing Tezepelumab in Adult Patients With Oral Corticosteroid Dependent Asthma
​
​
Mechanism: Anti-TSLP
LITHOS
Utilization of Budesonide and Formoterol Fumarate Metered Dose Inhaler Relative to Budesonide Metered Dose Inhaler in Adult and Adolescent Patients With Inadequately Controlled Asthma
​
​
CONTACT US
Chronic Cough Clinical Research Studies
CALM
Utilizing BLU-5937 in Adult Participants with Refractory Chronic Cough, Including Unexplained Chronic Cough
​
Mechanism: P2X3 receptor antagonist
​
Idiopathic Pulmonary Fibrosis Clinical Research Studies
HARBOUR
Utilizing HZN-825 in Subjects with Idiopathic Pulmonary Fibrosis
​
Mechanism: LPAR1-specific Antagonist
​