Clinical Trials
AIM-4
This study is researching a drug called dupilumab. The study is focused on patients who have uncontrolled asthma. The aim of the study is to see which regimen is more effective: taking dupilumab with an inhaled asthma medication or only taking a higher dose of the inhaled asthma medication. The type of asthma medication that will be used is a combination inhaled corticosteroid and long-acting beta-agonist (referred to as an ICS/LABA).
Disease Under Study
ASTHMA
Enrollment Status
OPEN
ASPIRE
This is a phase 2b, randomized, double-blind, placebo-controlled study investigating the efficacy, safety, and tolerability of Taplucainium Inhalation Powder (NOC-110) once daily in adults with refractory or unexplained chronic cough.
Disease Under Study
Chronic Cough
Enrollment Status
OPEN
ARRIVAL
Open-label Study to Assess Reduction of Background Asthma Medication While Sustaining Asthma Control and Clinical Remission With Tezepelumab in Patients 12-80yrs With Severe Asthma.
Disease Under Study
ASTHMA
Enrollment Status
OPEN
AMGEN
A Phase 2, Randomized, Double-blind, Placebo-controlled, Dose Ranging Study to Assess the Efficacy and Safety of Rocatinlimab in Adult Subjects With Moderate-to-severe Asthma
Disease Under Study
ASTHMA
Enrollment Status
OPEN
MIST
A randomized, double-blind, placebo-controlled clinical study to evaluate the safety and efficacy of 2 doses of inhaled pirfenidone (AP01) versus placebo on top of standard of care in participants with PPF over 52 weeks.
Disease Under Study
Progressive Pulmonary Fibrosis
Enrollment Status
OPEN
MIRANDA
Evaluating the efficacy and safety of tozorakimab in symptomatic Chronic Obstructive Pulmonary Disease with a history of exacerbations
Disease Under Study
COPD
Enrollment Status
CLOSED
TRANSFORM
Idiopathic Pulmonary Fibrosis is a chronic lung disease which causes scarring of the lungs and difficulty in breathing. GSK3915393 is a new medicine, which is being tested in participants with IPF for the first time. The study will assess the safety and effectiveness of GSK3915393 in IPF participants.
Disease Under Study
Idiopathic Pulmonary Fibrosis
Enrollment Status
OPEN
EXHALE-2
A randomized, double-blind, placebo-controlled, parallel-group study to assess the efficacy, safety, and tolerability of dexpramipexole administered orally for 52 weeks in participants with severe eosinophilic asthma (EXHALE-2)
Disease Under Study
ASTHMA
Enrollment Status
OPEN
EXHALE-4
A Randomized, Double-blind, Placebo-controlled, Parallel-group Study to Assess the Efficacy, Safety, and Tolerability of Dexpramipexole Administered Orally for 24 Weeks in Participants With Eosinophilic Asthma
Disease Under Study
ASTHMA
Enrollment Status
CLOSED
TEVA FpA-AS-30094
A Study to Test if a Fixed-Dose Combination of Fluticasone Propionate/Albuterol Sulfate is Effective in Preventing Asthma Exacerbations
Disease Under Study
ASTHMA
Enrollment Status
OPEN
VALIANT
The purpose of this study is to evaluate the efficacy and safety of verekitug (UPB-101) in participants with severe asthma. The study will evaluate the incidence of asthma exacerbations, other pharmacodynamic (PD) parameters such as lung function and asthma control, and the safety and tolerability of verekitug (UPB-101) compared to placebo.
Disease Under Study
ASTHMA
Enrollment Status
OPEN
CORAL
Cough Reduction in Idiopathic Pulmonary Fibrosis (IPF) With Nalbuphine Extended Release Capsules
Disease Under Study
Chronic Cough associated with Idiopathic Pulmonary Fibrosis
Enrollment Status
CLOSED
TETON
Evaluating the safety and efficacy of inhaled treprostinil in subjects with progressive pulmonary fibrosis (PPF) over a 52-week period.
Disease Under Study
Progressive Pulmonary Fibrosis
Enrollment Status
OPEN
THARROS
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
Disease Under Study
COPD
Enrollment Status
OPEN
MOONSCAPE
A Study Evaluating the Efficacy and Safety of Vixarelimab in Participants With Idiopathic Pulmonary Fibrosis and in Participants With Systemic Sclerosis-Associated Interstitial Lung Disease
Disease Under Study
Idiopathic Pulmonary Fibrosis
Enrollment Status
CLOSED
INCYTE
A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Inadequately Controlled Moderate to Severe Asthma
Disease Under Study
ASTHMA
Enrollment Status
CLOSED
BEACON
PLN-74809, is an oral once daily antifibrotic being studied for the treatment of idiopathic pulmonary fibrosis (IPF).
Disease Under Study
Idiopathic Pulmonary Fibrosis
Enrollment Status
CLOSED
CALM-1
Utilizing BLU-5937 in Adult Participants with Refractory Chronic Cough, Including Unexplained Chronic Cough
Disease Under Study
Chronic Cough
Enrollment Status
CLOSED
SUNRISE
Utilizing Tezepelumab in Adult Patients With Oral Corticosteroid Dependent Asthma
Disease Under Study
ASTHMA
Enrollment Status
CLOSED
ATLAS
Assessing the Long-term Effect of Dupilumab on Prevention of Lung Function Decline in Patients With Uncontrolled Moderate to Severe Asthma
Disease Under Study
ASTHMA
Enrollment Status
OPEN
NIMBLE
Utilization of Depemokimab Compared With Mepolizumab or Benralizumab in Participants With Severe Asthma With an Eosinophilic Phenotype
Disease Under Study
ASTHMA
Enrollment Status
CLOSED
KALOS
Utilization of Budesonide, Glycopyrronium, and Formoterol Fumarate metered dose inhaler relative to Budesonide and Formoterol Fumarate MDI and Symbicort® pressurized MDI in patients with inadequately controlled asthma
Disease Under Study
ASTHMA
Enrollment Status
CLOSED